Gene sequencing refers to determining the precise sequence of nucleotides in a DNA molecule fragment, helping scientists decipher genetic information. Up to now, gene sequencing technology has gone through three generations of development: the first generation of sequencing began in 1977, when Professor Frederick Sanger invented the dideoxy chain termination method, which had low throughput and high cost; The second generation sequencing, also known as high-throughput sequencing, began around 2005. It enabled scientists to sequence large amounts of DNA fragments in parallel, greatly improving sequencing speed and efficiency; The third-generation sequencing technology, namely single-molecule sequencing, began around 2008 and can directly read continuous sequences of tens or even hundreds of thousands of bases, further improving sequencing speed. Gene sequencer is the core equipment of gene sequencing. With the joint promotion of scientific breakthroughs and technological progress, gene sequencer has become increasingly efficient and economical. It can be said that the history of the advancement of gene sequencers is also the history of the development of gene sequencing. By comparing.
